Publications 2018
Aarts SABM, Reiche ME, den Toom M, Beckers L, Gijbels MJJ, Gerdes N, de Winther MPJ, Lutgens E (2018). Macrophage CD40 plays a minor role in obesity-induced metabolic dysfunction. PLoS One. 13:e0202150. PMID 30096208. [A5]
Atzler D, de Winther MPJ (2018). DARC matter(s) for inflammatory cells. Cardiovasc Res. 114:e11-e13. PMID 29373721. [A5]
Baardman J, Verberk SGS, Prange KHM, van Weeghel M, van der Velden S, Ryan DG, Wüst RCI, Neele AE, Speijer D, Denis SW, Witte ME, Houtkooper RH, O'neill LA, Knatko EV, Dinkova-Kostova AT, Lutgens E, de Winther MPJ, van den Bossche J (2018). A defective pentose phosphate pathway reduces inflammatory macrophage responses during hypercholesterolemia. Cell Rep. 25:2044-2052.e5. PMID 30463003. [A5]
Baaten CCFMJ, Meacham S, de Witt SM, Feijge MAH, Adams DJ, Akkerman JN, Cosemans JMEM, Grassi L, Jupe S, Kostadima M, Mattheij NJA, Prins MH, Ramirez-Solis R, Soehnlein O, Swieringa F, Weber C, White JK, Ouwehand WH, Heemskerk JWM (2018). A synthesis approach of mouse studies to identify genes and proteins in arterial thrombosis and bleeding. Blood. 132:e35-e46. PMID 30275110. [A6, B5]
Bahls M, Atzler D, Markus MRP, Friedrich N, Böger RH, Völzke H, Felix SB, Schwedhelm E, Dörr M (2018). Low-circulating homoarginine is associated with dilatation and decreased function of the left ventricle in the general population. Biomolecules. 8:63. PMID 30061520. [A5]
Baldassarri F, Schwedhelm E, Atzler D, Böger RH, Cordts K, Haller B, Pressler A, Müller S, Suchy C, Wachter R, Düngen HD, Hasenfuss G, Pieske B, Halle M, Edelmann F, Duvinage A (2018). Relationship between exercise intervention and NO pathway in patients with heart failure with preserved ejection fraction. Biomarkers. 23:540-550. PMID 29619838. [A5]
Bartelt A, Behler-Janbeck F, Beil FT, Koehne T, Müller B, Schmidt T, Heine M, Ochs L, Yilmaz T, Dietrich M, Tuckermann JP, Amling M, Herz J, Schinke T, Heeren J, Niemeier A (2018). Lrp1 in osteoblasts controls osteoclast activity and protects against osteoporosis by limiting PDGF-RANKL signaling. Bone Res. 6:4. PMID 29507818. [B10]
Bartelt A*, Widenmaier SB*, Schlein C, Johann K, Goncalves RLS, Eguchi K, Fischer AW, Parlakgül G, Snyder NA, Nguyen TB, Bruns OT, Franke D, Bawendi MG, Lynes MD, Leiria LO, Tseng YH, Inouye KE, Arruda AP, Hotamisligil GS (2018). Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity. Nat Med. 24:292-303. PMID 29400713 *shared first authors [B10]
Braza MS, van Leent MMT, Lameijer M, Sanchez-Gaytan BL, Arts RJW, Pérez-Medina C, Conde P, Garcia MR, Gonzalez-Perez M, Brahmachary M, Fay F, Kluza E, Kossatz S, Dress RJ, Salem F, Rialdi A, Reiner T, Boros P, Strijkers GJ, Calcagno CC, Ginhoux F, Marazzi I, Lutgens E, Nicolaes GAF, Weber C, Swirski FK, Nahrendorf M, Fisher EA, Duivenvoorden R, Fayad ZA, Netea MG, Mulder WJM, Ochando J (2018). Inhibiting inflammation with myeloid cell-specific nanobiologics promotes organ transplant acceptance. Immunity. 49:819-828.e6. PMID 30413362. [A1, A10]
Busygina K, Jamasbi J, Seiler T, Deckmyn H, Weber C, Brandl R, Lorenz R, Siess W (2018). Oral bruton tyrosine kinase inhibitors selectively block atherosclerotic plaque-triggered thrombus formation. Blood. 131:2605-2616. PMID 29559479. [A1, A10]
Caporali A, Bäck M, Daemen MJ, Hoefer IE, Jones EA, Lutgens E, Matter CM, Bochaton-Piallat ML, Siekmann AF, Sluimer JC, Steffens S, Tuñón J, Vindis C, Wentzel JJ, Ylä-Herttuala S, Evans PC (2018). Future directions for therapeutic strategies in post-ischaemic vascularization: a position paper from European society of cardiology working group on atherosclerosis and vascular biology. Cardiovasc Res. 114:1411-1421. PMID 30016405. [A5, B9]
Casanova-Acebes M, Nicolás-Ávila JA, Li JL, García-Silva S, Balachander A, Rubio-Ponce A, Weiss LA, Adrover JM, Burrows K, A-González N, Ballesteros I, Devi S, Quintana JA, Crainiciuc G, Leiva M, Gunzer M, Weber C, Nagasawa T, Soehnlein O, Merad M, Mortha A, Ng LG, Peinado H, Hidalgo A (2018). Neutrophils instruct homeostatic and pathological states in naive tissues. J Exp Med. 215:2778-2795. PMID 30282719. [A1, A6, A10, B5]
Chevre R, Silvestre-Roig C, Soehnlein O (2018). Nutritional modulation of innate immunity: the fat-bile-gut connection. Trends Endocrinol Metab. 29:686-698. PMID 30197155. [A6, B5]
Christ A, Günther P, Lauterbach MAR, Duewell P, Biswas D, Pelka L Scholz CJ, Oosting M, Haendler K, Baßler K, Klee K, Schulte-Schrepping J, Ulas T, Moorlag SJCFM, Kumar V, Park MH, Joosten LAB, Groh LA, Riksen NP, Espevik T, Schlitzer A, Li Y, Fitzgerald ML, Netea MG, Schultze JL, Latz E (2018). Western diet triggers NLRP3-dependent innate immune reprogramming. Cell. 172:162-175. PMID 29328911. [B7]
*Clemmensen C, Jall S, Kleinert M, Quarta C, Gruber T, Reber J, Sachs S, Fischer K, Feuchtinger A, Karlas A, Simonds SE, Grandl G, Loher D, Sanchez-Quant E, Keipert S, Jastroch M, Hofmann SM, Nascimento EBM, Schrauwen P, Ntziachristos V, Cowley MA, Finan B, Müller TD, Tschöp MH (2018). Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes. Nat Commun. 9:4304. PMID 30353008. [A4, Z1]
Curaj A, Wu Z, van Zandvoort M, Gresch O, Weber C, Lammers T, Liehn EA, Kiessling F (2018). Molecular ultrasound imaging of the junctional adhesion molecule-A depicts acute changes in blood flow and its effect on endothelial activation. Arterioscler. Thromb. Vasc. Biol. 38:40-48. PMID 29191926. [A1, A10]
Damby DE, Horwell CJ, Baxter PJ, Kueppers U, Schnurr M, Dingwell DB, Duewell P (2018). Volcanic ash activates the NLRP3 inflammasome in murine and human macrophages. Front Immunol. 8:2000. PMID 29403480. [B7]
Daugherty A, Lu HS, Hegele RA, Mackman N, Rader DJ, Schmidt AM, Weber C (2018). Response by Daugherty et al to Letter regarding article, "Consideration of sex differences in design and reporting of experimental arterial pathology studies: a statement from the Arteriosclerosis, Thrombosis, and Vascular Biology Council". Arterioscler Thromb Vasc Biol. 38:e101-e102. PMID 29793996. [A1, A10]
Den Harder AM, de Jong PA, de Groot MCH, Wolterink JM, Budde RPJ, Iŝgum I, van Solinge WW, Ten Berg MJ, Lutgens E, Veldhuis WB, Haitjema S, Hoefer IE, Leiner T (2018). Commonly available hematological biomarkers are associated with the extent of coronary calcifications. Atherosclerosis. 275:166-173. PMID 29920437. [A5]
Di Francesco A, Fedrigo M, Santovito D, Natarelli L, Castellani C, De Pascale F, Toscano G, Fraiese A, Feltrin G, Benazzi E, Nocco A, Thiene G, Valente M, Valle G, Schober A, Gerosa G, Angelini A (2018). MicroRNA signatures in cardiac biopsies and detection of allograft rejection. J Heart Lung Transplant. 37:1329-1340. PMID 30174164. [B4]
Döring Y, van der Vorst EPC (2018). Gouty offense in patients with obstructive coronary artery disease despite state-of-the-art therapy. J Am Heart Assoc. 7:e010322. PMID 30369331. [A1]
Domschke G, Linden F, Pawig L, Hafner A, Akhavanpoor M, Reymann J, Doesch AO, Erbel C, Weber C, Katus HA, Noels H, Erfle H, Gleissner CA, Runz H (2018). Systematic RNA-interference in primary human monocyte-derived macrophages: A high-throughput platform to study foam cell formation. Sci Rep. 8:10516. PMID 30002403. [A1, A10]
Dorn T, Kornherr J, Parrotta EI, Zawada D, Ayetey H, Santamaria G, Iop L, Mastantuono E, Sinnecker D, Goedel A, Dirschinger RJ, My I, Laue S, Bozoglu T, Baarlink C, Ziegler T, Graf E, Hinkel R, Cuda G, Kääb S, Grace AA, Grosse R, Kupatt C, Meitinger T, Smith AG, Laugwitz KL, Moretti A (2018). Interplay of cell-cell contacts and RhoA/MRTF-A signaling regulates cardiomyocyte identity. EMBO J. 37:e98133. PMID 29764980. [C3]
Ebrahim M, Jamasbi J, Adler K, Megens RTA, M’Bengue Y, Blanchet X, Uhland K, Ungerer M, Brandl R, Weber C, Elia N, Lorenz R, Münch G, Siess W (2018). Dimeric glycoprotein VI binds to collagen but not to fibrin. Thromb Haemost. 118:351-361. PMID 29378359. [A1, A10, Z1]
Eikendal ALM, Bots ML, Gohar A, Lutgens E, Hoefer IE, den Ruijter HM, Leiner T (2018). Circulating levels of P-selectin and E-selectin relate to cardiovascular magnetic resonance-derived aortic characteristics in young adults from the general population, a cross-sectional study. J Cardiovasc Magn Reson. 20:54. PMID 30068374. [A5]
Faller KME*, Atzler D*, McAndrew DJ, Zervou S, Whittington HJ, Simon JN, Aksentijevic D, Ten Hove M, Choe CU, Isbrandt D, Casadei B, Schneider JE, Neubauer S, Lygate CA (2018). Impaired cardiac contractile function in arginine:glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine. Cardiovasc Res. 114:417-430. PMID 29236952. *shared first authors [A5]
Franceschini N, Giambartolomei C, de Vries PS, Finan C, Bis JC, Huntley RP, Lovering RC, Tajuddin SM, Winkler TW, Graff M, Kavousi M, Dale C, Smith AV, Hofer E, van Leeuwen EM, Nolte IM, Lu L, Scholz M, Sargurupremraj M, Pitkänen N, Franzén O, Joshi PK, Noordam R, Marioni RE, Hwang SJ, Musani SK, Schminke U, Palmas W, Isaacs A, Correa A, Zonderman AB, Hofman A, Teumer A , Cox AJ, Uitterlinden AG , Wong A, Smit AJ, Newman AB, Britton A, Ruusalepp A, Sennblad B, Hedblad B, Pasaniuc B, Penninx BW, Langefeld CD, Wassel CL, Tzourio C, Fava C , Baldassarre D , O'Leary DH, Teupser D, Kuh D, Tremoli E, Mannarino E, Grossi E, Boerwinkle E, Schadt EE, Ingelsson E, Veglia F, Rivadeneira F, Beutner F, Chauhan G , Heiss G, Snieder H, Campbell H, Völzke H, Markus HS, Deary IJ, Jukema JW, de Graaf J, Price J, Pott J, Hopewell JC, Liang J, Thiery J, Engmann J, Gertow K, Rice K, Taylor KD, Dhana K, Kiemeney LALM, Lind L, Raffield LM, Launer LJ, Holdt LM, Dörr M, Dichgans M, Traylor M, Sitzer M, Kumari M, Kivimaki M , Nalls MA, Melander O, Raitakari O , Franco OH, Rueda-Ochoa OL, Roussos P, Whincup PH, Amouyel P, Giral P, Anugu P, Wong Q, Malik R, Rauramaa R, Burkhardt R, Hardy R, Schmidt R, de Mutsert R, Morris RW, Strawbridge RJ, Wannamethee SG, Hägg S, Shah S, McLachlan S, Trompet S, Seshadri S, Kurl S, Heckbert SR, Ring S, Harris B, Lehtimäki T, Galesloot TE, Shah T, de Faire U, Plagnol V, Rosamond WD, Post W, Zhu X, Zhang X, Guo X, Saba Y, MEGASTROKE Consortium; Dehghan A, Seldenrijk A, Morrison AC, Hamsten A, Psaty BM, van Duijn CM, Lawlor DA , Mook-Kanamori DO, Bowden DW , Schmidt H, Wilson JF, Wilson JG, Rotter JI , Wardlaw JM, Deanfield J, Halcox J, Lyytikäinen LP, Loeffler M, Evans MK, Debette S, Humphries SE, Völker U, Gudnason V, Hingorani AD, Björkegren JLM, Casas JP, O'Donnell CJ (2018). GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Nat Commun. 9:5141. PMID 30510157. [B1, B3]
Gao Y, Lehti M, Donelan E, Al-Massadi O, Chandler R, Weber J, Yi YX, Woods SC, Tschöp MH, Hofmann SM (2018). Circulating HDL levels control hypothalamic astrogliosis via ApoA-I. J Lipid Res. 59:1649-1659. PMID 29991652. [A4]
Götz A, Lehti M, Donelan E, Striese C, Cucuruz S, Sachs S, Yi CX, Woods SC, Wright SD, Müller TD, Tschöp MH, Gao Y, Hofmann SM (2018). Circulating HDL levels control hypothalamic astrogliosis via apoA-I. J Lipid Res. 59:1649-1659. PMID 29991652. [A4]
Grebe A, Hoss F, Latz E (2018). NLRP3 inflammasome and the IL-1 pathway in atherosclerosis. Circ Res. 122:1722-1740. PMID 29880500. [B7]
Hinkel R, Klett K, Bähr A, Kupatt C (2018). Thymosin β4-mediated protective effects in the heart. Expert Opin Biol Ther. 18:121-129. PMID 30063857. [C3]
Holdt LM, Kohlmaier A, Teupser D (2018b). Circular RNAs as therapeutic agents and targets. Front Physiol. 9:1262. PMID 30356745.
Holdt LM, Kohlmaier A, Teupser D (2018). Molecular functions and specific roles of circRNAs in the cardiovascular system. Noncoding RNA Res. 3:75-98. PMID 30159442. [B1]
Holdt LM, Kohlmaier A, Teupser D (2018). Molecular roles and function of circular RNAs in eukaryotic cells. Cell Mol Life Sci. 75:1071-1098. PMID 29116363. [B1]
Holdt LM, Teupser D (2018). Long noncoding RNA ANRIL: Lnc-ing genetic variation at the chromosome 9p21 locus to molecular mechanisms of atherosclerosis. Front Cardiovasc Med. 5:145. PMID 30460243. [B1]
Hoogeveen RM, Nahrendorf M, Riksen NP, Netea MG, de Winther MPJ, Lutgens E, Nordestgaard B, Neidhart M, Stroes ESG, Catapano AL, Bekkering S (2018). Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases. Eur Heart J. 39:3521-3527. PMID 29069365. [A5]
Horckmans M, Bianchini M, Santovito D, Megens RTA, Springael JY, Negri I, Vacca M, Di Eusanio M, Moschetta A, Weber C, Duchêne J, Steffens S (2018). Pericardial adipose tissue regulates granulopoiesis, fibrosis, and car-diac function after myocardial infarction. Circulation. 137:948-960. PMID 29167227. [A1, A10, B9, Z1]
Jin H, Li DY, Chernogubova E, Sun C, Busch A, Eken SM, Saliba-Gustafsson P, Winter H, Winski G, Raaz U, Schellinger IN, Simon N, Hegenloh R, Matic LP, Jagodic M, Ehrenborg E, Pelisek J, Eckstein HH, Hedin U, Backlund A, Maegdefessel L (2018). Local delivery of miR-21 stabilizes fibrous caps in vulnerable atherosclerotic lesions. Mol Ther. 26:1040-1055. PMID 29503197. [B5]
Kellnberger S, Soliman D, Tserevelakis GJ, Seeger M, Yang H, Karlas A, Prade L, Ntziachristos V (2018). Optoacoustic microscopy at multiple discrete frequencies. Light Sci Appl. 7:109. PMID 30588294. [Z1]
Kuipers EN, Kantae V, Maarse BCE, van den Berg SM, van Eenige R, Nahon KJ, Reifel-Miller A, Coskun T, de Winther MPJ, Lutgens E, Kooijman S, Harms AC, Hankemeier T, van der Stelt M, Rensen PCN, Boon MR (2018). High fat diet increases circulating endocannabinoids accompanied by increased synthesis enzymes in adipose tissue. Front Physiol. 9:1913. PMID 30687125. [A5]
Kusters PJH, Seijkens TTP, Beckers L, Lievens D, Winkels H, de Waard V, Duijvestijn A, Lindquist Liljeqvist M, Roy J, Daugherty A, Newby A, Gerdes N, Lutgens E (2018). CD40L deficiency protects against aneurysm formation. Arterioscler Thromb Vasc Biol. 38:1076-1085. PMID 29519940. [A5]
Kusters PJH, Lutgens E, Seijkens TTP (2018). Exploring immune checkpoints as potential therapeutic targets in atherosclerosis. Cardiovasc Res. 114:368-377. PMID 29309533. [A5]
Längin M, Mayr T, Reichart B, Michel S, Buchholz S, Guethoff S, Dashkevich A, Baehr A, Egerer S, Bauer A, Mihalj M, Panelli A, Issl L, Ying J, Fresch AK, IButtgereit I, Mokelke M, Radan J, Werner F, Lutzmann I, Steen S, Sjöberg T, Paskevicius A, Qiuming L, Sfriso R, Rieben R, Dahlhoff M, Kessler B, Kemter E, Klett K, Hinkel R, Kupatt C, Falkenau A, Reu S, Ellgass R, Herzog R, Binder U, Wich G, Skerra A, Ayares D, Kind A, Schönmann U, Kaup FJ, Hagl C, Wolf E, Klymiuk N, Brenner P, Abicht JM (2018). Consistent success in life-supporting porcine cardiac xenotransplantation. Nature. 564:430-433. PMID 30518863. [C3]
Lameijer M, Binderup T, van Leent MMT, Senders ML, Fay F, Malkus J, Sanchez-Gaytan BL, Teunissen AJP, Karakatsanis N, Robson P, Zhou X, Ye Y, Wojtkiewicz G, Tang J, Seijkens TTP, Kroon J, Stroes ESG, Kjaer A, Ochando J, Reiner T, Pérez-Medina C, Calcagno C, Fisher EA, Zhang B, Temel RE, Swirski FK, Nahrendorf M, Fayad ZA, Lutgens E, Mulder WJM, Duivenvoorden R (2018). Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates. Nat Biomed Eng. 2:279-292. PMID 31015637. [A5]
Leoni G, Soehnlein O (2018). (Re) solving repair after myocardial infarction. Front Pharmacol. 9:1342. PMID 30534069. [A6, B5]
Li DY, Busch A, Jin H, Chernogubova E, Pelisek J, Karlsson J, Sennblad B, Liu S, Lao S, Hofmann P, Bäcklund A, Eken SM, Roy J, Eriksson P, Dacken B, Ramanujam D, Dueck A, Engelhardt S, Boon RA, Eckstein HH, Spin JM, Tsao PS, Maegdefessel L (2018). H19 Induces abdominal aortic aneurysm development and progression. Circulation. 138:1551-1568. PMID 29669788. [B5]
Lu HS, Schmidt AM, Hegele RA, Mackman N, Rader DJ, Weber C, Daugherty A (2018). Reporting sex and sex differences in preclinical studies. Arterioscler Thromb Vasc Biol. 38:e171-e184. PMID 30354222. [A1, A10]
Maas SL, Soehnlein O and Viola JR (2018). Organ-specific mechanisms of transendothelial neutrophil migration in the lung, liver, kidney, and aorta. Front. Immunol. 9:2739. PMID 30538702. [A6, B5]
Mak'Anyengo M, Duewell P, Reichl C, Hörth C, Lehr HA, Fischer S, Clavel T, Denk G, Hohenester S, Kobold S, Endres S, Schnurr M, Bauer C (2018). Nlrp3-dependent IL-1β inhibits CD103+ dendritic cell differentiation in the gut. JCI Insight. 3:e96322. PMID 29515025. [B7]
Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Bena-vente OR, Bevan S, Boncoraglio GB, Brown RD Jr, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, den Hoed M, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jiménez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O'Donnell MJ, Psaty BM, Pulit SL, Rannikmäe K, Reiner AP, Rexrode KM, Rice K, Rich SS, Ridker PM, Rost NS, Rothwell PM, Rotter JI, Rundek T, Sacco RL, Sakaue S, Sale MM, Salomaa V, Sapkota BR, Schmidt R, Schmidt CO, Schminke U, Sharma P, Slowik A, Sudlow CLM, Tanislav C, Tatlisumak T, Taylor KD, Thijs VNS, Thorleifsson G, Thorsteinsdottir U, Tiedt S, Trompet S, Tzourio C, van Duijn CM, Walters M, Wareham NJ, Wassertheil-Smoller S, Wilson JG, Wiggins KL, Yang Q, Yusuf S; AFGen Consortium; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium; International Genomics of Blood Pressure (iGEN-BP) Consortium; INVENT Consortium; STARNET, Bis JC, Pastinen T, Ruusalepp A, Schadt EE, Koplev S, Björkegren JLM, Codoni V, Civelek M, Smith NL, Trégouët DA, Christophersen IE, Roselli C, Lubitz SA, Ellinor PT, Tai ES, Kooner JS, Kato N, He J, van der Harst P, Elliott P, Chambers JC, Takeuchi F, Johnson AD; BioBank Japan Cooperative Hospital Group; COMPASS Consortium; EPIC-CVD Consortium; EPIC-InterAct Consortium; Interna-tional Stroke Genetics Consortium (ISGC); METASTROKE Consortium; Neurology Working Group of the CHARGE Consortium; NINDS Stroke Genetics Network (SiGN); UK Young Lacunar DNA Study; MEGASTROKE Consortium, Sanghera DK, Melander O, Jern C, Strbian D, Fernandez-Cadenas I, Longstreth WT Jr, Rolfs A, Hata J, Woo D, Rosand J, Pare G, Hopewell JC, Saleheen D, Stefansson K, Worrall BB, Kittner SJ, Seshadri S, Fornage M, Markus HS, Howson JMM, Kamatani Y, Debette S, Dichgans M (2018). Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Nat Genet. 50:524-537. PMID 29531354. [B3]
Natarelli L, Geissler C, Csaba G, Wei Y, Zhu M, di Francesco A, Hartmann P, Zimmer R, Schober A (2018). Mir-103 promotes endothelial maladaptation by targeting lncwdr59. Nat Commun. 9:2645. PMID 29980665. [B4, Z2]
Neele AE, Gijbels MJJ, van der Velden S, Hoeksema MA, Boshuizen MCS, Prange KHM, Chen HJ, Van den Bossche J, van Roomen CPPA, Shami A, Levels JHM, Kroon J, Lucas T, Dimmeler S, Lutgens E, de Winther MPJ (2018). Myeloid Kdm6b deficiency results in advanced atherosclerosis. Atherosclerosis. 275:156-165. PMID 29908485. [A5]
Nicolaou A, Northoff BH, Zhao Z, Kohlmaier A, Sass K, Rose-John S, Steffens S, Weber C, Teupser D, Holdt LM (2018).The ADAM17 metalloproteinase maintains arterial elasticity. Thromb Haemost. 118:210-213. PMID 29304540. [A1, A10, B1, B9]
Niekamp C, Atzler D, Ojeda FM, Sinning CR, Lackner KJ, Böger RH, Munzel T, Beutel ME, Schmidtmann I, Pfeiffer N, Leuschner A, Blankenberg S, Wild PS, Zeller T, Schwedhelm E, Schnabel RB (2018). Cross-sectional associations between homoarginine, intermediate phenotypes, and atrial fibrillation in the community-the Gutenberg Health Study. Biomolecules. 8:e86. PMID 30200232. [A5]
Novotny J, Chandraratne S, Weinberger T, Philipp V, Stark K, Ehrlich A, Pircher J, Pelisek J, Massberg S, von Brühl ML, Schulz C (2018). Histological comparison of arterial thrombi in mice and men. PLos One. 13:e0190728. PMID 29293656. [A7, B6]
Pacher P, Steffens S, Haskó G, Schindler TH, Kunos G (2018). Cardiovascular effects of marijuana and synthetic cannabinoids: the good, the bad, and the ugly. Nat Rev Cardiol. 15:151-166. PMID 28905873. [B9]
Patel J, Lutgens E (2018). Scientists on the spot: Esther Lutgens on the immune system and atherosclerosis. Cardiovasc Res. 114:e113. PMID 30476016. [A5]
Paulin N, Viola JR, Maas SL, de Jong R, Fernandes-Alnemri T, Weber C, Drechsler M, Döring Y*, Soehnlein O* (2018). Double-strand DNA sensing Aim2 inflammasome regulates atherosclerotic plaque vulnerability. Circulation. 138:321–323. PMID 30012706. *equal contribution [A1, A6, A10, B5]
Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, Grommes J, Saha P, Titova A, Ishikawa-Ankerhold H, Stark K, Petzold T, Stocker T, Weckbach LT, Novotny J, Sperandio M, Nieswandt B, Smith A, Mannell H, Walzog B, Horst D, Soehnlein O, Massberg S, Schulz C (2018). Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation. Nat Commun. 9:1523. PMID 29670076. [A6, A7, B5, B6]
Poh PS, Schmauss V, McGovern JA, Schmauss D, Theodoropoulos C, Chhaya MP, Foehr P, Seeger M, Ntziachristos V, Hutmacher DW, van Griensven M, Schantz JT, Balmayor ER (2018). Non-linear optical microscopy and histological analysis of collagen, elastin and lysyl oxidase expression in breast capsular contracture. Eur J Med Res. 23:30. PMID 29866167. [Z1]
Poller W, Dimmeler S, Heymans S, Zeller T, Haas J, Karakas M, Leistner DM, Jakob P, Nakagawa S, Blankenberg S, Engelhardt S, Thum T, Weber C, Meder B, Hajjar R, Landmesser U (2018). Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives. Eur Heart J. 39:2704-2716. PMID 28430919. [A1, A10]
Rami M, Guillamat-Prats R, Rinne P, Salvermoser M, Ring L, Bianchini M, Blanchet X, Megens RTA, Döring Y, Walzog B, Soehnlein O, Weber C, Faussner A, Steffens S (2018). Chronic intake of the selective serotonin reuptake inhibitor Fluoxetine enhances atherosclerosis. Arterioscler Thromb Vasc Biol. 38:1007-1019. PMID 29567680. [A1, A6, A10, B5, B9, Z1]
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