Publications 2016

Atzler D, Schönhoff M, Cordts K, Ortland I, Hoppe J, Hummel FC, Gerloff C, Jaehde U, Jagodzinski A, Böger RH, Choe CU, Schwedhelm E (2016). Oral supplementation with L-homoarginine in young volunteers. Br J Clin Pharmaco. 82:1477-1485. PMID 27434056. [A5]

Bamberg F, Hetterich H, Rospleszcz S, Lorbeer R, Auweter SD, Schlett CL, Schafnitzel A, Bayerl C, Schindler A, Saam T, Müller-Peltzer K, Sommer W, Zitzelsberger T, Machann J, Ingrisch M, Selder S, Rathmann W, Heier M, Linkohr B, Meisinger C, Weber C, Ertl-Wagner B, Massberg S, Reiser MF, Peters A (2016). Subclinical disease burden as assessed by whole-body MRI in subjects with prediabetes, subjects with diabetes, and normal control subjects from the general population: the KORA-MRI study. Diabetes. 66:158-169. PMID 27999110. [A1, A1, B6]

Bauer C, Kühnemuth B, Duewell P, Ormanns S, Gress T, Schnurr M (2016). Prevailing over T cell exhaustion: New developments in the immunotherapy of pancreatic cancer. Cancer Lett. 381:259-68. PMID 26968250. [B7]

Berchtold E, Csaba G, Zimmer R (2016). Evaluating transcription factor activity changes by scoring unexplained target genes in expression data. PLoS One. 11:e0164513. PMID 27723775. [Z2]

Braster Q, Silvestre Roig C, Hartwig H, Beckers L, den Toom M, Döring Y, Daemen MJ, Lutgens E, Soehnlein O (2016). Inhibition of NET release fails to reduce adipose tissue inflammation in mice. PLoS One. 11:e0163922. PMID 27701440. [A1, A5, A6, B5]

Braster Q, Silvestre-Roig C, Hartwig H, Kusters P, Aarts S, den Toom M, Gallo RL, Weber C, Lutgens E, Soehnlein O (2016). Cathelicidin regulates myeloid cell accumulation in adipose tissue and promotes insulin resistance during obesity. Thromb Haemost. 115:1237-9. PMID 26939624 [A1, A5, A6, A10, B5]

Cabrera-Fuentes HA, Alba-Alba C, Aragones J, Bernhagen J, Boisvert WA, Bøtker HE, Cesarman-Maus G, Fleming I, Garcia-Dorado D, Lecour S, Liehn E, Marber MS, Marina N, Mayr M, Perez-Mendez O, Miura T, Ruiz-Meana M, Salinas-Estefanon EM, Ong SB, Schnittler HJ, Sanchez-Vega JT, Sumoza-Toledo A, Vogel CW, Yarullina D, Yellon DM, Preissner KT, Hausenloy DJ (2016). Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside. Basic Res Cardiol. 111:7. PMID 26667317. [A3]

Cabrera-Fuentes HA, Aragones J, Bernhagen J, Boening A, Boisvert WA, Bøtker HE, Bulluck H, Cook S, Di Lisa F, Engel FB, Engelmann B, Ferrazzi F, Ferdinandy P, Fong A, Fleming I, Gnaiger E, Hernández-Reséndiz S, Kalkhoran SB, Kim MH, Lecour S, Liehn EA, Marber MS, Mayr M, Miura T, Ong SB, Peter K, Sedding D, Singh MK, Suleiman MS, Schnittler HJ, Schulz R, Shim W, Tello D, Vogel CW, Walker M, Li QO, Yellon DM, Hausenloy DJ, Preissner KT (2016). From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on "New frontiers in cardiovascular research". Basic Res Cardiol. 111:69. PMID 27743118. [A3]

Campa CC, Germena G, Ciraolo E, Copperi F, Sapienza A, Franco I, Ghigo A, Camporeale A, Di SavinoA, Martini M, Perino A, Megens RTA, Kurz AR, Scheiermann C, Sperandio M, Gamba A, Hirsch E (2016). Rac signal adaptation controls neutrophil mobilization from the bone marrow. Sci Signal. 20:9. PMID 27999173. [Z1]

Chong SZ, Evrard M, Devi S, Chen J, Lim JY, See P, Zhang Y, Adrover JM, Lee B, Tan L, Li JL, Liong KH, Phua C, Balachander A, Boey A, Liebl D, Tan SM, Chan JK, Balabanian K, Harris JE, Bianchini M, Weber C, Dûchene J, Lum J, Poidinger M, Chen Q, Rénia L, Wang CI, Larbi A, Randolph GJ, Weninger W, Looney MR, Krummel MF, Biswas SK, Ginhoux F, Hidalgo A, Bachelerie F, Ng LG (2016). CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses. J Exp Med. 213:2293-2314. PMID 27811056. [A1, A10]

Chubanov V, Ferioli S, Wisnowsky A, Simmons DG, Leitzinger C, Einer C, Jonas W, Shymkiv Y, Bartsch H, Braun A, Akdogan B, Mittermeier L, Sytik L, Torben F, Jurinovic V, van der Vorst EPC, Weber C, Yildirim ÖA, Sotlar K, Schürmann A, Zierler S, Zischka H, Ryazanov AG, Gudermann T (2016). Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. eLife. 5:e20914. PMID 27991852. [A1, A10, C2]

Daugherty A, Hegele RA, Mackman N, Rader DJ, Schmidt AM, Weber C (2016). Complying with the national institutes of health guidelines and principles for rigor and reproducibility: refutations. Arterioscler Thromb Vasc Biol. 36:1303-4. PMID 27335467. [A1, A10]

De Jong RJ, Leoni G, Drechsler M, Soehnlein O (2016). The advantageous role of annexin A1 in cardiovascular disease. Cell Adh Migr. 18:1-14. PMID 27860536. [A6, B5]

Deppe J, Popp T, Egea V, Steinritz D, Schmidt A, Thiermann H, Weber C, Ries C (2016). Impairment of hypoxia-induced HIF-1α signaling in keratinocytes and fibroblasts by sulfur mustard is counteracted by a selective PHD-2 inhibitor. Arch Toxicol. 90:1141-50. PMID 26082309. [A1, A10]

Deppe J, Steinritz D, Santovito D, Egea V, Schmidt A, Weber C, Ries C (2016). Upregulation of miR-203 and miR-210 affect growth and differentiation of keratinocytes after exposure to sulfur mustard in normoxia and hypoxia. Toxicol Lett. 244:81-7. PMID 26383628. [A1, A10]

El Bounkari O, Bernhagen J (2016). Discovery of a startling star: chemotaxis and chemotactic inhibition by starfish MIFs. Immunol Cell Biol. 94:313-314. PMID 27089827. [A3]

Finan B, Clemmensen C, Zhu Z, Stemmer K, Gauthier K, Müller L, De Angelis M, Moreth K, Neff F, Perez-Tilve D, Fischer K, Lutter D, Sánchez-Garrido MA, Liu P, Tuckermann J, Malehmir M, Healy ME, Weber A, Heikenwalder M, Jastroch M, Kleinert M, Jall S, Brandt S, Flamant F, Schramm KW, Biebermann H, Döring Y, Weber C, Habegger KM, Keuper M, Gelfanov V, Liu F, Köhrle J, Rozman J, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Hofmann SM, Yang B, Tschöp MH, DiMarchi R, Müller TD (2016). Chemical hybridization of glucagon and thyroid hormone optimizes therapeutic impact for metabolic disease. Cell. 167:843-857. PMID 27720451. [A1, A4, A10]

Gamrekelashvili J, Giagnorio R, Jussofie J, Soehnlein O, Dûchene J, Briseño CG, Ramasamy SK, Krishnasamy K, Limbourg A, Kapanadze T, Ishifune C, Hinkel R, Radtke F, Strobl LJ, Zimber-Strobl U, Napp LC, Bauersachs J, Haller H, Yasutomo K, Kupatt C, Murphy KM, Adams RH, Weber C, Limbourg FP (2016). Regulation of monocyte cell fate by blood vessels mediated by notch signalling. Nat Commun. 31:7-12. PMID 27576369. [A1, A6, A10, B5, C3]

García-Cáceres C, Quarta C, Varela L, Gao Y, Gruber T, Legutko B, Jastroch M, Johansson P, Ninkovic J, Yi CX, Le Thuc O, Szigeti-Buck K, Cai W, Meyer CW, Pfluger PT, Fernandez AM, Luquet S, Woods SC, Torres-Alemán I, Kahn CR, Götz M, Horvath TL, Tschöp MH (2016). Astrocytic insulin signaling couples brain glucose uptake with nutrient availability. Cell. 166:867-880. PMID 27518562. [A4]

Geistlinger L, Csaba G, Zimmer R. Bioconductor's EnrichmentBrowser: seamless navigation through combined results of set- & network-based enrichment analysis. BMC Bioinformatics. 17:45. PMID 26791995. [Z2]

Gerdes N, Seijkens T, Lievens D, Kuijpers MJ, Winkels H, Projahn D, Hartwig H, Beckers L, Megens RTA, Boon L, Noelle RJ, Soehnlein O, Heemskerk JW, Weber C, Lutgens E (2016). Platelet CD40 exacerbates atherosclerosis by transcellular activation of endothelial cells and leukocytes. Arterioscler Thromb Vasc Biol. 36:482-90. PMID 26821950. [A1, A5, A6, A10, B5, Z1]

Hartmann P, Zhou Z, Natarelli L, Wei Y, Nazari-Jahantigh M, Zhu M, Grommes J, Steffens S, Weber C, Schober A (2016). Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4. Nat Commun. 7:10521. PMID 26837267. [A1, A10, B4, B9]

Hartmann D, Fiedler J, Sonnenschein K, Just A, Pfanne A, Zimmer K, Remke J, Foinquinos A, Butzlaff M, Schimmel K, Maegdefessel L, Hilfiker-Kleiner D, Lachmann N, Schober A, Froese N, Heineke J, Bauersachs J, Batkai S, Thum T (2016). MicroRNA-based therapy of gata2-deficient vascular disease. Circulation. 13:1973-1990. PMID 27780851. [B4, B5]

Hibender S, Franken R, van Roomen C, Ter Braake A, van der Made I, Schermer EE, Gunst Q, van den Hoff MJ, Lutgens E, Pinto YM, Groenink M, Zwinderman AH, Mulder BJ, de Vries CJ, de Waard V (2016). Resveratrol inhibits aortic root dilatation in the Fbn1C1039G/+ marfan mouse model. Arterioscler Thromb Vasc Biol. 36:1618-26. PMID 27283746. [A5]

Holdt LM, Stahringer A, Sass K, Pichler G, Kulak NA, Wilfert W, Kohlmaier A, Herbst A, Northoff BH, Nicolaou A, Gäbel G, Beutner F, Scholz M, Thiery J, Musunuru K, Krohn K, Mann M, Teupser D (2016). Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans. Nat Commun. 7:12429. PMID 27539542. [B1]

Hu D, Yin C, Mohanta SK, Weber C, Habenicht AJ (2016). Preparation of single cell suspensions from mouse aorta. Bio Protoc. 11:5-7. PMID 27335895. [A1, A10, C2]

Jamasbi J, Megens RTA, Bianchini M, Uhland K, Münch G, Ungerer M, Sherman S, Faussner A, Brandl R, John C, Buchner J, Weber C, Lorenz R, Elia N, Siess W (2016). Cross-linking GPVI-Fc by anti-Fc antibodies potentiates its inhibition of atherosclerotic plaque- and collagen-induced platelet activation. JACC Basic Transl Sci. 1:142-13. PMID 27766315. [A1, A10, Z1]

Jansen M, Hollander M, van Royen, N, Horrevoets AJ, Lutgens E (2016). CD40 in coronary artery disease: a matter of macrophages? Basic Res Cardiol. 111:38. PMID 27146510. [A5]

Kessler T, Erdmann J, Vilne B, Bruse P, Kurowski V, Diemert P, Schunkert H, Sager HB (2016). Serum microRNA-1233 is a specific biomarker for diagnosing acute pulmonary embolism. J Transl Med. 14:120. PMID 27150028. [B2, C1]

Kessler T, Vilne B, Schunkert H (2016). The impact of genome-wide association studies on the pathophysiology and therapy of cardiovascular disease. EMBO Mol Med. 8:688-701. PMID 27189168. [B2]

Khera AV, Won HH, Peloso GM, Lawson KS, Bartz TM, Deng X, van Leeuwen EM, Natarajan P, Emdin CA, Bick AG, Morrison AC, Brody JA, Gupta N, Nomura A, Kessler T, Duga S, Bis JC, van Duijn CM, Cupples LA, Psaty B, Rader DJ, Danesh J, Schunkert H, McPherson R, Farrall M, Watkins H, Lander E, Wilson JG, Correa A, Boerwinkle E, Merlini PA, Ardissino D, Saleheen D, Gabriel S, Kathiresan S (2016). Diagnostic yield and clinical utility of sequencing familial hypercholesterolemia genes in patients with severe hypercholesterolemia. J Am Coll Cardiol. 67:2578-89. PMID 27050191. [B2]

LeBlanc M, Zuber V, Andreassen BK, Witoelar A, Zeng L, Bettella F, Wang Y, McEvoy LK, Thompson WK, Schork AJ, Reppe S, Barrett-Connor E, Ligthart S, Dehghan A, Gautvik KM, Nelson CP, Schunkert H, Samani NJ; CARDIoGRAM Consortium, Ridker PM, Chasman DI, Aukrust P, Djurovic S, Frigessi A, Desikan RS, Dale AM, Andreassen OA (2016). Identifying novel gene variants in coronary artery disease and shared genes with several cardiovascular risk factors. Circ Res. 118:83-94. PMID 26487741. [B2]

Li J, McArdle S, Gholami A, Kimura T, Wolf D, Gerhardt T, Miller J, Weber C, Ley K (2016). CCR5+T-bet+FoxP3+ Effector CD4 T cells drive atherosclerosis. Circ Res. 13:1540-52. PMID 27021296. [A1, A10]

Mahl C, Egea V, Megens RTA, Pitsch T, Santovito D, Weber C, Ries C (2016). RECK (reversion-inducing cysteine-rich protein with Kazal motifs) regulates migration, differentiation and Wnt/β-catenin signaling in human mesenchymal stem cells. Cell Mol Life Sci. 73:1489-501. PMID 26459448. [A1, A10, Z1]

Meiler S, Smeets E, Winkels H, Shami A, Pascutti MF, Nolte MA, Beckers L, Weber C, Gerdes N, Lutgens E (2016). Constitutive GITR activation reduces atherosclerosis by promoting regulatory CD4+ T cell responses. Arterioscler Thromb Vasc Biol. 36:1748-52. PMID 27444204. [A1, A5, A10]

Mohanta SK, Yin C, Weber C, Hu D, Habenicht AJ (2016). Aorta atherosclerosis lesion analysis in hyperlipidemic mice. Bio Protoc. 6:e1833. PMID 27366759. [A1, A10, C2]

Mühlstedt S, Ghadge SK, Dûchene J, Qadri F, Järve A, Vilianovich L, Popova E, Pohlmann A, Niendorf T, Boyé P, Özcelik C, Bader M (2016). Cardiomyocyte-derived CXCL12 is not involved in cardiogenesis but plays a crucial role in myocardial infarction. J Mol Med. 94:1005-14. PMID 27251706. [A10]

Müller M, Kessler T, Schunkert H, Erdmann J, Tennstedt S (2016). Classification of ADAMTS binding sites: The first step toward selective ADAMTS7 inhibitors. Biochem Biophys Res Commun. 471:380-5. PMID 26872430. [B2]

Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators, Stitziel NO, Stirrups KE, Masca NG, Erdmann J, Ferrario PG, König IR, Weeke PE, Webb TR, Auer PL, Schick UM, Lu Y, Zhang H, Dube MP, Goel A, Farrall M, Peloso GM, Won HH, Do R, van Iperen E, Kanoni S, Kruppa J, Mahajan A, Scott RA, Willenberg C, Braund PS, van Capelleveen JC, Doney AS, Donnelly LA, Asselta R, Merlini PA, Duga S, Marziliano N, Denny JC, Shaffer CM, El-Mokhtari NE, Franke A, Gottesman O, Heilmann S, Hengstenberg C, Hoffman P, Holmen OL, Hveem K, Jansson JH, Jöckel KH, Kessler T, Kriebel J, Laugwitz KL, Marouli E, Martinelli N, McCarthy MI, Van Zuydam NR, Meisinger C, Esko T, Mihailov E, Escher SA, Alver M, Moebus S, Morris AD, Müller-Nurasyid M, Nikpay M, Olivieri O, Lemieux Perreault LP, AlQarawi A, Robertson NR, Akinsanya KO, Reilly DF, Vogt TF, Yin W, Asselbergs FW, Kooperberg C, Jackson RD, Stahl E, Strauch K, Varga TV, Waldenberger M, Zeng L, Kraja AT, Liu C, Ehret GB, Newton-Cheh C, Chasman DI, Chowdhury R, Ferrario M, Ford I, Jukema JW, Kee F, Kuulasmaa K, Nordestgaard BG, Perola M, Saleheen D, Sattar N, Surendran P, Tregouet D, Young R, Howson JM, Butterworth AS, Danesh J, Ardissino D, Bottinger EP, Erbel R, Franks PW, Girelli D, Hall AS, Hovingh GK, Kastrati A, Lieb W, Meitinger T, Kraus WE, Shah SH, McPherson R, Orho-Melander M, Melander O, Metspalu A, Palmer CN, Peters A, Rader D, Reilly MP, Loos RJ, Reiner AP, Roden DM, Tardif JC, Thompson JR, Wareham NJ, Watkins H, Willer CJ, Kathiresan S, Deloukas P, Samani NJ, Schunkert H (2016). Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease. N Engl J Med. 374:1134-44. PMID 26934567. [B2]

Noels H, Bernhagen J (2016). Editorial: The CXCR4 ligand/receptor family and the DPP4 protease in high-risk cardiovascular patients. Front Immunol. 7:58. PMID 26925063. [A3]

Ortega-Gomez A, Salvermoser M, Rossaint J, Pick R, Brauner J, Lemnitzer P, Tilgner J, de Jong RJ, Megens RTA, Jamasbi J, Döring Y, Pham CT, Scheiermann C, Siess W, Drechsler M, Weber C, Grommes J, Zarbock A, Walzog B, Soehnlein O (2016). Cathepsin G controls arterial but not venular myeloid cell recruitment. Circulation. 134:1176-1188. PMID 27660294. [A1, A6, A10, B5, Z1]

Pasqualon T, Lue H, Groening S, Pruessmeyer J, Jahr H, Denecke B, Bernhagen J, Ludwig A (2016). Cell surface syndecan-1 contributes to binding and function of macro¬phage migration inhibitory factor (MIF) on epithelial tumor cells. Biochim Biophys Acta. 1863:717-726. PMID 26852939. [A3]

Peleg S, Feller C, Forne I, Schiller E, Sévin DC, Schauer T, Regnard C, Straub T, Prestel M, Klima C, Schmitt Nogueira M, Becker L, Klopstock T, Sauer U, Becker PB, Imhof A, Ladurner AG (2016). Life span extension by targeting a link between metabolism and histone acetylation in Drosophila. EMBO Reports. 17:455–469. PMID 26781291. [Z2]

Pesch R, Zimmer R. Cross-species conservation of context-specific networks. BMC Syst Biol. 10:76. PMID 27531214. [Z2]

Petzold T, Thienel M, Konrad I, Schubert I, Regenauer R, Hoppe B, Lorenz M, Eckart A, Chandraratne S, Lennerz C, Kolb C, Braun D, Jamasbi J, Brandl R, Braun S, Siess W, Schulz C, Massberg S (2016). Oral thrombin inhibitor aggravates platelet adhesion and aggregation during arterial thrombosis. Sci Transl Med. 8:367ra168. PMID 27903864. [A7, B6]

Pfeiler S, Khandagale AB, Magenau A, Nichols M, Heijnen HF, Rinninger F, Ziegler T, Seveau S, Schubert S, Zahler S, Verschoor A, Latz E, Massberg S, Gaus K, Engelmann B (2016). Distinct surveillance pathway for immunopathology during acute infection via autophagy and SR-BI. Sci Rep. 6:34440. PMID 27694929. [B6, B7]

Przybyl L, Haase N, Golic M, Rugor J, Solano ME, Arck PC, Gauster M, Huppertz B, Emontzpohl C, Stoppe C, Bernhagen J, Leng L, Bucala R, Schulz H, Heuser A, Weedon-Fekjær MS, Johnsen GM, Peetz D, Luft FC, Staff AC, Müller DN, Dechend R, Herse F (2016). CD74-downregulation of placental macrophage-trophoblastic interactions in preeclampsia. Circ Res. 119:55-68. PMID 27199465. [A3]

Rajasekaran D, Gröning S, Schmitz C, Zierow S, Drucker N, Bakou M, Kohl K, Mertens A, Lue H, Weber C, Xiao A, Luker G, Kapurniotu A, Lolis E, Bernhagen J (2016). MIF-CXCR4 receptor interactions: evidence for partial allosteric agonism in comparison with CXCL12 chemokine. J Biol Chem. 291:15881-895. PMID 27226569. [A1, A3, A10]

Roger T, Schneider A, Weier M, Sweep FC, Le Roy D, Bernhagen J, Calandra T, Giannoni E (2016). High expression levels of macrophage migration inhibitory factor sustain the innate immune responses of neonates. Proc Natl Acad Sci U S A. 113:E997-1005. PMID 26858459. [A3]

Rohm M, Schäfer M, Laurent V, Üstünel BE, Niopek K, Algire C, Hautzinger O, Sijmonsma TP, Zota A, Medrikova D, Pellegata NS, Ryden M, Kulyte A, Dahlman I, Arner P, Petrovic N, Cannon B, Amri EZ, Kemp BE, Steinberg GR, Janovska P, Kopecky J, Wolfrum C, Blüher M, Berriel Diaz M, Herzig S (2016). An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice. Nat Med. 22:1120-1130. PMID 27571348. [B9]

Sager HB et al. (2016). RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction. Sci Transl Med. 8:342ra80. PMID 27280687. [C1]

Sager HB, Hulsmans M, Lavine KJ, Moreira MB, Heidt T, Courties G, Sun Y, Iwamoto Y, Tricot B, Khan OF, Dahlman JE, Borodovsky A, Fitzgerald K, Anderson DG, Weissleder R, Libby P, Swirski FK, Nahrendorf M (2016). Proliferation and recruitment contribute to myocardial macrophage expansion in chronic heart failure. Circ Res. 119:853-64. PMID 27444755. [C1]

Santovito D, Egea V, Weber C (2016). Small but smart: MicroRNAs orchestrate atherosclerosis development and progression. Biochim Biophys Acta. 1861:2075-2086. PMID 26738655. [A1, A10]

Schaftenaar F, Frodermann V, Kuiper J, Lutgens E (2016). Atherosclerosis: the interplay between lipids and immune cells. Curr Opin Lipidol. 27:209-15. PMID 27031276. [A5]

Schloss MJ, Horckmans M, Nitz K, Duchêne J, Drechsler M, Bidzhekov K, Scheiermann C, Weber C, Soehnlein O, Steffens S (2016). The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment. EMBO Mol Med. 8:937-48. PMID 27226028. [A1, A6, A10, B5, B9]

Schmohl J, Santovito D, Guenther T, Sutanto W, Kroell T, Salih H, Pitsch T, Egea V, Weber C, Schmetzer H, Ries C (2016). Expression of surface-associated 82kDa-proMMP-9 in primary acute leukemia blast cells inversely correlates with patients' risk. Exp Hematol. 44:358-362. PMID 26845021. [A1, A10]

Schober A, Weber C (2016). Mechanisms of microRNAs in atherosclerosis. Annu Rev Pathol. 11:583-616. PMID 27193456. [A1, A10, B4]

Schöppner P, Csaba G, Braun T, Daake M, Richter B, Lange OF, Zacharias M, Zimmer R, Haslbeck M (2016). Regulatory implications of non-trivial splicing: Isoform 3 of Rab1A shows enhanced basal activity and is not controlled by accessory proteins. J Mol Biol. 428:1544-57. PMID 26953259. [Z2]

Seeger M, Karlas A, Soliman D, Pelisek J, Ntziachristos V (2016). Multimodal optoacoustic and multiphoton microscopy of human carotid atheroma. Photoacoustics. 4:102-111. PMID 27761409. [Z1]

Silvestre-Roig C, Hidalgo A, Soehnlein O (2016). Neutrophil heterogeneity: implications for homeostasis and pathogenesis. Blood. 127:2173-81. PMID 27002116. [A6, B5]

Simsekyilmaz S, Liehn EA, Weinandy S, Schreiber F, Megens RTA, Theelen W, Smeets R, Jockenhövel S, Gries T, Möller M, Klee D, Weber C, Zernecke A (2016). Trageting in-stent-stenosis with Rgd- and Cxcl1- coated mini-stents in mice. PLoS One. 11:e0155829. PMID 27192172. [A1, A10, Z1]

Soehnlein O (2016). Monocytes chat with atherosclerotic lesions. Arterioscler Thromb Vasc Biol. 6:1720-1. PMID 27559145. [A6, B5]

Spitz C, Winkels H, Bürger C, Weber C, Lutgens E, Hansson GK, Gerdes N (2016). Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential. Cell Mol Life Sci. 73:901-22. PMID 26518635. [A1, A5, A10]

Spronck B, Megens RTA, Reesink KD, Delhaas T (2016). A method for three-dimensional quantification of vascular smooth muscle orientation: application in viable murine carotid arteries. Biomech Model Mechanobiol. 15:419-32. PMID 26174758. [Z1]

Srikakulapu P*, Hu D*, Yin C*, Mohanta SK*, Bontha SV, Peng L, Beer M, Weber C, McNamara CA, Grassia G, Maffia P, Manz RA, Habenicht AJR (2016). Artery tertiary lymphoid organs control multilayered territorialized atherosclerosis B-cell responses in aged ApoE-/- mice. Arterioscler Thromb Vasc Biol. 36:1174-85. PMID 27102965; *shared first authors [A1, A10, C2]

Stark K, Philippi V, Stockhausen S, Busse J, Antonelli A, Miller M, Schubert I, Hoseinpour P, Chandraratne S, von Brühl ML, Gaertner F, Lorenz M, Agresti A, Coletti R, Antoine DJ, Heermann R, Jung K, Reese S, Laitinen I, Schwaiger M, Walch A, Sperandio M, Nawroth PP, Reinhardt C, Jäckel S, Bianchi ME, Massberg S (2016). Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice. Blood. 128:2435-2449. PMID 27574188. [B6]

Steffens S (2016). M1 signature mediators in atheroma-derived single cell secretome of symptomatic plaques. Thromb Haemost. 115:871. PMID 27052888. [B9]

Tilgner J, von Trotha KT, Gombert A, Jacobs MJ, Drechsler M, Döring Y, Soehnlein O, Grommes J (2016). Aspirin but not tirofiban displays protective effects in endotoxin induced lung injury. PLoS One. 11:e0161218. PMID 27583400. [A1, A6, B5]

Tzoumas S, Nunes A, Olefir I, Stangl S, Symvoulidis P, Glasl S, Bayer C, Multhoff G, Ntziachristos V (2016). Eigenspectra optoacoustic tomography achieves quantitative blood oxygenation imaging deep in tissues. Nat Commun. 7:12121. PMID 27358000. [Z1]

Van Dam AD, Bekkering S, Crasborn M, van Beek L, van den Berg SM, Vrieling F, Joosten SA, van Harmelen V, de Winther MP, Lütjohann D, Lutgens E, Boon MR, Riksen NP, Rensen PC, Berbée JF (2016). BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice. Atherosclerosis. 251:6-14. PMID 27232458. [A5]

Van den Berg S, Seijkens TTP, Kusters PJH, Beckers L, den Toom M, Smeets E, Levels J, de Winther M, Lutgens E (2016). Diet induced obesity in mice diminishes hematopoietic stem and progenitor cells in the bone marrow. FASEB. 30:1779-1788. PMID 26813974. [A5]

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