Publications 2021
Abdel Rahman F, d'Almeida S, Zhang T, Asadi M, Bozoglu T, Bongiovanni D, von Scheidt M, Dietzel S, Schwedhelm E, Hinkel R, Laugwitz KL, Kupatt C, Ziegler T (2021). Sphingosine-1-Phosphate attenuates Lipopolysaccharide-induced pericyte loss via activation of Rho-A and MRTF-A. Thromb Haemost. 121:341-350. PMID 33011963. [C3]
Alexander Y, Osto E, Schmidt-Trucksass A, Shechter M, Trifunovic D, Duncker DJ, Aboyans V, Back M, Badimon L, Cosentino F, De Carlo M, Dorobantu M, Harrison DG, Guzik TJ, Hoefer I, Morris PD, Norata GD, Suades R, Taddei S, Vilahur G, Waltenberger J, Weber C, Wilkinson F, Bochaton-Piallat ML, Evans PC (2021). Endothelial function in cardiovascular medicine: a consensus paper of the european society of cardiology working groups on atherosclerosis and vascular biology, aorta and peripheral vascular diseases, coronary pathophysiology and, microcirculation, and thrombosis. Cardiovasc Res. 117:29-42. PMID 32282914. [A1, A10]
Barkaway A, Rolas L, Joulia R, Bodkin J, Lenn T, Owen-Woods C, Reglero-Real N, Stein M, Vazquez-Martinez L, Girbl T, Poston RN, Golding M, Saleeb RS, Thiriot A, von Andrian UH, Duchêne J, Voisin MB, Bishop CL, Voehringer D, Roers A, Rot A, Lammermann T, Nourshargh S (2021). Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage. Immunity. 54:1494-1510 e1497. PMID 34033752. [A10]
Bernlochner I, Klug M, Larasati D, Von Scheidt M, Santovito D, Hristov M, Weber C, Laugwitz KL, Bongiovanni D (2021). Sorting and magnetic-based isolation of reticulated platelets from peripheral blood. Platelets. 32:113-119. PMID 32046562. [A1, A10]
Bosmans LA, Bosch L, Kusters PJH, Lutgens E, Seijkens TTP (2021). The CD40-CD40L dyad as immunotherapeutic target in cardiovascular disease. J Cardiovasc Transl Res. 14:13-22. PMID 32222950. [A5]
Bosmans LA, Shami A, Atzler D, Weber C, Goncalves I, Lutgens E (2021). Glucocorticoid induced TNF receptor family-related protein (GITR) - A novel driver of atherosclerosis. Vascul Pharmacol. 139:106884. PMID 34102305. [A1, A5, A10]
Brandhofer M, (24 authors), von Hundelshausen P, Bernhagen J (2021). Heterocomplexes between the atypical chemokine MIF and the CXC-motif chemokine CXCL4L1 regulate inflammation and thrombus formation. bioRxiv. doi 10.1101/2021.11.26.470090. [A2, A3]
Busch A, Pauli J, Winski G, Bleichert S, Chernogubova E, Metschl S, Winter H, Trenner M, Wiegering A, Otto C, Fischer J, Reiser J, Werner J, Roy J, Brostjan C, Knappich C, Eckstein HH, Paloschi V, Maegdefessel L (2021). Lenvatinib halts aortic aneurysm growth by restoring smooth muscle cell contractility. JCI Insight. 6:140364. PMID 34185710. [B5]
Carai P, Papageorgiou AP, Van Linthout S, Deckx S, Velthuis S, Lutgens E, Wijnands E, Tschope C, Schmuttermaier C, Kzhyshkowska J, Jones EAV, Heymans S (2021). Stabilin-1 mediates beneficial monocyte recruitment and tolerogenic macrophage programming during CVB3-induced viral myocarditis. J Mol Cell Cardiol. 165:31-39. PMID 34968453. [A5]
Chondronikola M, Bartelt A, Vidal-Puig A, Virtanen KA (2021). Editorial: brown adipose tissue: from heat production in rodents to metabolic health in humans. Front Endocrinol. 12:739065. PMID 34381425. [B10]
Chirivi RGS, van Rosmalen JWG, van der Linden M, Euler M, Schmets G, Bogatkevich G, Kambas K, Hahn J, Braster Q, Soehnlein O, Hoffmann MH, Es H, Raats JMH (2021). Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases. Cell Mol Immunol. 18:1528-1544. PMID 32203195. [A6, B5]
Dang TA*, Kessler T*, Wobst J, Wierer M, Braenne I, Strom TM, Tennstedt S, Sager HB, Meitinger T, Erdmann J, Schunkert H (2021). Identification of a functional PDE5A variant at the chromosome 4q27 coronary artery disease locus in an extended myocardial infarction family. Circulation. 144:662-665. * equal contribution. PMID 34424768. [B2, C1]
Datta-Chaudhuri T, Zanos T, Chang EH, Olofsson PS, Bickel S, Bouton C, Grande D, Rieth L, Aranow C, Bloom O, Mehta AD, Civillico G, Stevens MM, Glowacki E, Bettinger C, Schuettler M, Puleo C, Rennaker R, Mohanta S, Carnevale D, Conde SV, Bonaz B, Chernoff D, Kapa S, Berggren M, Ludwig K, Zanos S, Miller L, Weber D, Yoshor D, Steinman L, Chavan SS, Pavlov VA, Al-Abed Y, Tracey KJ (2021). The fourth Bioelectronic Medicine Summit "Technology Targeting Molecular Mechanisms": current progress, challenges, and charting the future. Bioelectron Med. 7:7. PMID 34024277. [C2]
Davidson SM, Padro T, Bollini S, Vilahur G, Duncker DJ, Evans PC, Guzik T, Hoefer IE, Waltenberger J, Wojta J, Weber C (2021). Progress in cardiac research: from rebooting cardiac regeneration to a complete cell atlas of the heart. Cardiovasc Res. 117:2161-2174. PMID 34114614. [A1, A10]
Döring Y, (20 authors), Weber C (2021). CCL17 signals through CCR8 to induce CCL3 expression and restrain atheroprotective Tregs. Open Data LMU. doi 10.5282/ubm/data.279. [A1, A10]
Duan R, Goldmann L, Brandl R, Spannagl M, Weber C, Siess W, von Hundelshausen P (2021). Effects of the Btk-inhibitors remibrutinib (LOU064) and rilzabrutinib (PRN1008) with varying Btk selectivity over Tec on platelet aggregation and in vitro bleeding time. Front Cardiovasc Med. 8:749022. PMID 34631841. [A1, A2, A10]
Duan R, Goldmann L, Li Y, Weber C, Siess W, von Hundelshausen P (2021). Spontaneous platelet aggregation in blood is mediated by FcgammaRIIA stimulation of Bruton's Tyrosine Kinase. Int J Mol Sci. 23. PMID 35008508. [A1, A2, A10]
Egea V, Kessenbrock K, Lawson D, Bartelt A, Weber C, Ries C (2021). Let-7f miRNA regulates SDF-1alpha- and hypoxia-promoted migration of mesenchymal stem cells and attenuates mammary tumor growth upon exosomal release. Cell Death Dis. 12:516. PMID 34016957. [A1, A10, B10]
El Bounkari O#, Zan C#, (13 authors), Megens RTA, Weber C, Kapurniotu A, Bernhagen J* (2021). MIF-2/D-DT is an atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis. bioRxiv. doi 10.1101/2021.12.28.474328. [A1, A2, A10, Z1]
Evans P, Wojta J, Hoefer IE, Waltenberger J, Guzik T, Badimon L, Weber C (2021). The year in basic vascular biology research: from mechanoreceptors and nets to smartphone data and omics. Cardiovasc Res. 117:1814-1822. PMID 33744925. [A1, A10]
Fasolo F, Jin H, Winski G, Chernogubova E, Pauli J, Winter H, Li DY, Glukha N, Bauer S, Metschl S, Wu Z, Koschinsky ML, Reilly M, Pelisek J, Kempf W, Eckstein HH, Soehnlein O, Matic L, Hedin U, Bäcklund A, Bergmark C, Paloschi V, Maegdefessel L (2021). Long noncoding RNA MIAT controls advanced atherosclerotic lesion for-mation and plaque destabilization. Circulation. 144:1567-1583. PMID 34647815. [A6, B5]
Fidler TP, Xue C, Yalcinkaya M, Hardaway B, Abramowicz S, Xiao T, Liu W, Thomas DG, Hajebrahimi MA, Pircher J, Silvestre-Roig C, Kotini AG, Luchsinger LL, Wei Y, Westerterp M, Snoeck HW, Papapetrou EP, Schulz C, Massberg S, Soehnlein O, Ebert B, Levine RL, Reilly MP, Libby P, Wang N, Tall AR (2021). The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis. Nature. 592:296-301. PMID 33731931. [A6, A7, B5, B6]
Gäbel G, Northoff BH, Balboa A, Becirovic-Agic M, Petri M, Busch A, Maegdefessel L, Mahlmann A, Ludwig S, Teupser D, de Waard V, Golledge J, Wanhainen A, Wågsäter D, Holdt LM, Lindeman JHN (2021). Parallel murine and human aortic wall genomics reveals metabolic reprogramming as key driver of abdominal aortic aneurysm progression. J Am Heart Assoc. 10:e020231. PMID 34420357. [B1, B5]
Gencer S, Evans BR, van der Vorst EPC, Döring Y*, Weber C* (2021a). Inflammatory chemokines in atherosclerosis. Cells. 10:226. PMID 33503867. [A1, A10, C2]
Gencer S, Döring Y, Jansen Y, Bayasgalan S, Schengel O, Muller M, Peters LJF, Weber C, van der Vorst EPC (2021b). Adipocyte-specific ACKR3 regulates lipid levels in adipose tissue. Biomedicines. 9:394. PMID 33917642. [A1, A10, C2]
Gencer S, Evans BR, van der Vorst EPC, Döring Y, Weber C (2021). Inflammatory chemokines in atherosclerosis. Cells. 10:226. PMID 33503867. [A1, A10, C2]
Georgakis MK, Malik R, Li X, Gill D, Levin MG, Vy HMT, Judy R, Ritchie M, Verma SS; Regeneron Genetics Center, Nadkarni GN, Damrauer SM, Theodoratou E, Dichgans M (2021). Genetically downregulated interleukin-6 signal-ing is associated with a favorable cardiometabolic profile: a phenome-wide association study. Circulation. 143:1177-1180. PMID 33720771. [B3]
Georgakis MK*, van der Laan SW*, Asare Y, Mekke JM, Haitjema S, Schoneveld AH, de Jager SCA, Nurmohamed NS, Kroon J, Stroes ESG, de Kleijn DPV, de Borst GJ, Maegdefessel L, Soehnlein O, Pasterkamp G, Dichgans M (2021). Monocyte-chemoattractant protein-1 levels in human atherosclerotic lesions associate with plaque vulnerability. Arterioscler Thromb Vasc Biol. 41:2038-2048. PMID 33827260 *shared first authors [A6, B3, B5]
Georgiadi A, Lopez-Salazar V, Merahbi RE, Karikari RA, Ma X, Mourão A, Klepac K, Bühler L, Alfaro AJ, Kaczmarek I, Linford A, Bosma M, Shilkova O, Ritvos O, Nakamura N, Hirose S, Lassi M, Teperino R, Machado J, Scheideler M, Dietrich A, Geerlof A, Feuchtinger A, Blutke A, Fischer K, Müller TD, Kessler K, Schöneberg T, Thor D, Horne-mann S, Kruse M, Nawroth P, Pivovarova-Ramich O, Pfeiffer AFH, Sattler M, Blüher M, Herzig S (2021). Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue. Nat Commun. 12:2999. PMID 34016966. [B9]
Giroud M, Tsokanos FF, Caratti G, Kotschi S, Khani S, Jouffe C, Vogl ES, Irmler M, Glantschnig C, Gil-Lozano M, Hass D, Khan AA, Garcia MR, Mattijssen F, Maida A, Tews D, Fischer-Posovszky P, Feuchtinger A, Virtanen KA, Beckers J, Wabitsch M, Uhlenhaut H, Blüher M, Tuckermann J, Scheideler M, Bartelt A*, Herzig S* (2021). HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling. Diabetologia. 64:1850-1865. PMID 34014371 *shared corresponding authors [B9, B10]
Gissler MC, Scherrer P, Anto Michel N, Pennig J, Hoppe N, Funer L, Hardtner C, Stachon P, Li X, Mitre LS, Marchini T, Madl J, Wadle C, Hilgendorf I, von Zur Muhlen C, Bode C, Weber C, Lutgens E, Wolf D, Gerdes N, Zirlik A, Willecke F (2021). Deficiency of endothelial CD40 induces a stable plaque phenotype and limits inflammatory cell recruitment to atherosclerotic lesions in mice. Thromb Haemost. 121:1530-1540. PMID 33618394. [A1, A5, A10]
Goncalves RLS, Schlame M, Bartelt A, Brand MD, Hotamisligil GS (2021). Cardiolipin deficiency in barth syndrome is not associated with increased superoxide/H2 O2 production in heart and skeletal muscle mitochondria. FEBS Lett. 595:415-432. PMID 33112430. [B10]
Guillamat-Prats R, Hering D, Rami M, Härdtner C, Santovito D, (7 authors), Enard W, Weber C, Maegdefessel L, Faussner A, Hilgendorf I, Steffens S (2021). GPR55 modulates atherosclerosis by regulating plasma cell maturation. bioRxiv. doi 10.1101/2021.12.20.473518. [A1, A10, B5, B9]
Gutjahr JC, Crawford KS, Jensen DR, Naik P, Peterson FC, Samson GPB, Legler DF, Duchêne J, Veldkamp CT, Rot A, Volkman BF (2021). The dimeric form of CXCL12 binds to atypical chemokine receptor 1. Sci Signal. 14:eabc9012. PMID 34404752. [A10]
Heindl S, Ricci A, Carofiglio O, Zhou Q, Arzberger T, Lenart N, Franzmeier N, Hortobagyi T, Nelson PT, Stowe AM, Denes A, Edbauer D, Liesz A (2021). Chronic T-cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies. J Exp Med. 218:e20202411. PMID 34037669. [C1]
Heinrichs D, Brandt EF, Fischer P, Köhncke J, Wirtz TH, Guldiken N, Djudjaj S, Boor P, Kroy D, Weiskirchen R, Bucala R, Wasmuth HE, Strnad P, Trautwein C, Bernhagen J, Berres ML. (2021). Unexpected pro-fibrotic effect of MIF in non-alcoholic steatohepatitis is linked to a shift in NKT cell populations. Cells. 10:252. PMID 33525493. [A3]
Henderson JM, Weber C, Santovito D (2021). Beyond self-recycling: cell-specific role of autophagy in atherosclerosis. Cells. 10:625. PMID 33799835. [A1, A10]
Hettwer J, Hinterdobler J, Miritsch B, Deutsch MA, Li X, Mauersberger C, Moggio A, Braster Q, Gram H, Robertson AAB, Cooper MA, Groß O, Krane M, Weber C, Koenig W, Soehnlein O, Adamstein NH, Ridker P, Schunkert H, Libby P, Kessler T, Sager HB (2021). Interleukin-1β suppression dampens inflammatory leukocyte production and uptake in atherosclerosis. Cardiovasc Res. doi: 10.1093/cvr/cvab337. PMID 34718444. [A1, A6, A10, B2, B5, C1]
He YY, Xie XM, Zhang HD, Ye J, Gencer S, van der Vorst EPC, Döring Y, Weber C, Pang XB, Jing ZC, Yan Y, Han ZY (2021). Identification of hypoxia induced metabolism associated genes in pulmonary hypertension. Front Pharmacol. 12:753727. PMID 34803695. [A1, A10, C2]
Hidalgo A, Libby P, Soehnlein O, Aramburu IV, Papayannopoulos V, Silvestre-Roig C (2021). Neutrophil extracellular traps: from physiology to pathology. Cardiovasc Res. cvab329. PMID 34648022. [A6, B5]
Hinkel R, Batkai S, Bahr A, Bozoglu T, Straub S, Borchert T, Viereck J, Howe A, Hornaschewitz N, Oberberger L, Jurisch V, Kozlik-Feldmann R, Freudenthal F, Ziegler T, Weber C, Sperandio M, Engelhardt S, Laugwitz KL, Moretti A, Klymiuk N, Thum T, Kupatt C (2021). AntimiR-132 attenuates myocardial hypertrophy in an animal model of percutaneous aortic constriction. J Am Coll Cardiol. 77:2923-2935. PMID 34112319. [A1, A10, C3]
Hinterdobler J, Schunkert H, Kessler T, Sager HB (2021a). Impact of acute and chronic psychosocial stress on vascular inflammation. Antioxid Redox Signal. 35:1531-1550. PMID 34293932. [B2, C1]
Hinterdobler J, Schott S, Jin H, Meesmann A, Steinsiek AL, Zimmermann AS, Wobst J, Müller P, Mauersberger C, Vilne B, Baecklund A, Chen CS, Moggio A, Braster Q, Molitor M, Krane M, Kempf WE, Ladwig KH, Hristov M, Hulsmans M, Hilgendorf I, Weber C, Wenzel P, Scheiermann C, Maegdefessel L, Soehnlein O, Libby P, Nahrendorf M, Schunkert H, Kessler T, Sager HB (2021). Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis. Eur Heart J. 42:4077-4088. PMID 34279021. [A1, A6, A10, B2, B5, C1]
Huang S, Blutke A, Feuchtinger A, Klemm U, Tom RZ, Hofmann SM, Stiel AC, Ntziachristos V (2021). Functional multispectral optoacoustic tomography imaging of hepatic steatosis development in mice. EMBO Mol Med. 13:e13490. PMID 34411447. [A4, Z1]
Ives A, Le Roy D, Theroude C, Bernhagen J, Roger T, Calandra T (2021). Macrophage migration inhibitory factor promotes the migration of dendritic cells through CD74 and the activation of the Src/PI3K/myosin II pathway. FASEB J. 35:e21418. PMID 33774873. [A3]
Kaiser R, Leunig A, Pekayvaz K, Popp O, Joppich M, Polewka V, Escaig R, Anjum A, Hoffknecht ML, Gold C, Brambs S, Engel A, Stockhausen S, Knottenberg V, Titova A, Haji M, Scherer C, Muenchhoff M, Hellmuth JC, Saar K, Schubert B, Hilgendorff A, Schulz C, Kääb S, Zimmer R, Hübner N, Massberg S, Mertins P, Nicolai L, Stark K (2021). Self-sustaining interleukin-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19. JCI Insight. 17:150862. PMID 34403366. [A7, B6, Z2]
Kassiteridi C, Cole JE, Griseri T, Falck-Hansen M, Goddard ME, Seneviratne AN, Green PA, Park I, Shami AG, Pattarabanjird T, Upadhye A, Taylor AM, Handa A, Channon KM, Lutgens E, McNamara CA, Williams RO, Monaco C (2021). CD200 limits monopoiesis and monocyte recruitment in atherosclerosis. Circ Res. 129:280-295. PMID 33975450. [A5]
Kessler T, Schunkert H (2021). Coronary artery disease genetics enlightened by genome-wide association studies. J Am Coll Cardiol Basic Transl Sci. 7:610–623. PMID 34368511. [B2]
Kluza E, Beldman TJ, Shami A, Scholl ER, Malinova TS, Grootemaat AE, van der Wel NN, Goncalves I, Huveneers S, Mulder WJM, Lutgens E (2021). Diverse ultrastructural landscape of atherosclerotic endothelium. Atherosclerosis. 339:35-45. PMID 34847419. [A5]
Kou J, Wang M, Shi J, Zhang H, Pu X, Song S, Yang C, Yan Y, Döring Y, Xie X, Pang X (2021). Curcumin reduces cognitive deficits by inhibiting neuroinflammation through the endoplasmic reticulum stress pathway in apolipoprotein E4 transgenic mice. ACS Omega. 6:6654-6662. PMID 33748578. [A1]
Krammer C, Kontos C, Dewor M, Hille K, Dalla Volta B, El Bounkari O, Tas K, Sinitski D, Brandhofer M, Megens RTA, Weber C, Schultz JR, Bernhagen J*, Kapurniotu A* (2021a). A MIF-derived cyclopeptide that inhibits MIF binding and atherogenic signaling via the chemokine Receptor CXCR2. Chembiochem. 22:1012-1019. PMID 33125165. [A1, A3, A10, Z1]
Krammer C#, Yang B#, Reichl S, Bolini V, Schulte C, Noels H, El Bounkari O, Kapurniotu A, Weber C, Mohanta S, Bernhagen J* (2021b). Link between aging and atheroprotection in Mif-deficient atherosclerotic mice. bioRxiv. doi 10.1101/2021.12.14.471281. [A1, A3, A10, C2]
Lacy M, Bürger C, Shami A, Ahmadsei M, Winkels H, Nitz K, van Tiel CM, Seijkens TTP, Kusters PJH, Karshovka E, Prange KHM, Wu Y, Brouns SLN, Unterlugauer S, Kuijpers MJE, Reiche ME, Steffens S, Edsfeldt A, Megens RTA, Heemskerk JWM, Goncalves I, Weber C, Gerdes N, Atzler D*, Lutgens E* (2021). Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease. Nat Commun. 12:3754. PMID 34145241. *shared corresponding authors [A1, A5, A10, B9, Z1]
Lahiri S, Aftab W, Walenta L, Strauss L, Poutanen M, Mayerhofer A, Imhof A (2021). MALDI-IMS combined with shotgun proteomics identify and localize new factors in male infertility. Life Sci Alliance. 4:e202000672. PMID 33408244. [Z2]
Lee, MW*, Luo EW*, Silvestre-Roig C*, Srinivasan Y, Akabori K, Lemnitzer P, Schmidt NW, Lai GH, Santangerlo CD, Soehnlein O§, Wong, GCL§ (2021). Apolipoprotein mimetic peptide inhibits neutrophil-driven inflammatory damage via membrane remodelling and suppression of cell lysis. ACS Nano. 15:15930-15939. PMID 34586780. *, § equal contribution [A6, B5]
Lemmer IL, Willemsen N, Hilal N, Bartelt A (2021). A guide to understanding ndoplasmic reticulum stress in metabolic disorders. Mol Metab. 47:101169. PMID 33484951. [B10]
Lip GYH, Rigby A, Weber C (2021). Looking back on 2020, looking forward to 2021. Thromb Haemost. 121:1-3. PMID 33477196. [A1, A10]
Lutgens E, Joffre J, van Os B, Ait-Oufella H (2021). Targeting cytokines and immune checkpoints in atherosclerosis with monoclonal antibodies. Atherosclerosis. 335:98-109. PMID 34593238. [A5]
Loft A, Alfaro AJ, Schmidt SF, Pedersen FB, Terkelsen MK, Puglia M, Chow KK, Feuchtinger A, Troullinaki M, Maida A, Wolff G, Sakurai M, Berutti R, Ekim Üstünel B, Nawroth P, Ravnskjaer K, Diaz MB, Blagoev B, Herzig S (2021). Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic com-munication. Cell Metab. 33:1685-1700.e9. PMID 34237252. [B9]
Maciuszek M, Ortega-Gomez A, Maas SL, Perretti M, Merritt A, Soehnlein O, Chapman TM (2021). Synthesis and evaluation of novel cyclopentane urea FPR2 agonists and their potential application in the treatment of cardiovascular inflammation. Eur J Med Chem. 214:113194. PMID 33548634. [A6, B5]
Maciuszek M, Ortega-Gomez A, Maas SL, Garrido-Mesa J, Ferraro B, Perretti M, Merritt A, Nicolaes GAF, Soehnlein O, Chapman TM (2021). Design, synthesis, and biological evaluation of novel pyrrolidinone small-molecule Formyl peptide receptor 2 agonists. Eur J Med Chem. 226:113805. PMID 34536667. [A6, B5]
Marquez AB, van der Vorst EPC, Maas SL (2021). Key chemokine pathways in atherosclerosis and their therapeutic potential. J Clin Med. 10:3825. PMID 34501271. [C2]
Mauersberger C, Sager HB, Wobst J, Dang TA, Lambrecht L, Koplev S, Stroth M, Bettaga N, Schlossmann J, Wunder F, Friebe A, Björkegren JLM, Dietz L, Sandner P, Soehnlein O, Schunkert H*, Kessler T* (2021). Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation. bioRxiv. doi 10.1101/2021.11.15.467680. *equal contribution [A6, B2, B5, C1]
Mayer K, Hein-Rothweiler R, Schüpke S, Janisch M, Bernlochner I, Ndrepepa G, Sibbing D, Gori T, Borst O, Hold-enrieder S, Kupka D, Petzold T, Bradaric C, Okrojek R, Leistner DM, Trippel TD, Münzel T, Landmesser U, Pieske B, Zeiher AM, Gawaz MP, Hapfelmeier A, Laugwitz KL, Schunkert H, Kastrati A, Massberg S (2021). Efficacy and safety of revacept, a novel lesion-directed competitive antagonist to platelet glycoprotein VI, in patients undergoing elective percutaneous coronary intervention for stable ischemic heart disease: the randomized, double-blind, pla-cebo-controlled ISAR-PLASTER phase 2 trial. JAMA Cardiol. 6:753-761. PMID 33787834. [B2, B6]
Muley C, Kotschi S, Bartelt A (2021). Role of ubiquilins for brown adipocyte proteostasis and thermogenesis. Front. Endocrinol. 12:739021. PMID 34650520. [B10]
Muley C, Bartelt A (2021). Fuse your mitochondria, lose appetite: an anorexic, anti-obesity sphingolipid. EMBO Mol Med. 13:e14618. PMID 34288516. [B10]
Natarelli L, Parca L, Mazza T, Weber C, Virgili F, Fratantonio D (2021). MicroRNAs and long non-coding RNAs as potential candidates to target specific motifs of SARS-CoV-2. Noncoding RNA. 7:14. PMID 33670580. [A1, A10]
Natarelli L, Virgili F, Weber C (2021). SARS-CoV-2, cardiovascular diseases, and noncoding RNAs: a connected triad. Int J Mol Sci. 22:12243. PMID 34830125. [A1, A10]
Neele AE, Chen HJ, Gijbels MJJ, van der Velden S, Hoeksema MA, Boshuizen MCS, Van den Bossche J, Tool AT, Matlung HL, van den Berg TK, Lutgens E, de Winther MPJ (2021). Myeloid Ezh2 deficiency limits atherosclerosis development. Front Immunol. 11:594603. PMID 33574814. [A5]
Neele AE, Chen HJ, Gijbels MJJ, van der Velden S, Hoeksema MA, Boshuizen MCS, van den Bossche J, Tool AT, Matlung HL, van den Berg TK, Lutgens E, de Winther (2021). Myeloid EZH2 deficiency limits atherosclerosis development. Front Immunol. 11:594603. PMID 33574814. [A5]
Nicolai L, Kaiser R, Escaig R, Hoffknecht ML, Anjum A, Leunig A, Pircher J, Ehrlich A, Lorenz M, Ishikawa-Ankerhold H, Aird WC, Massberg S, Gaertner F (2021). Single platelet and megakaryocyte morpho-dynamics uncovered by multicolor reporter mouse strains in vitro and in vivo. Haematologica. doi: 10.3324/haematol.2021.278896. PMID 34525794. [B6]
Nicolai L, Leunig A, Brambs S, Kaiser R, Joppich M, Hoffknecht ML, Gold C, Engel A, Polewka V, Muenchhoff M, Hellmuth JC, Ruhle A, Ledderose S, Weinberger T, Schulz H, Scherer C, Rudelius M, Zoller M, Keppler OT, Zwißler B, von Bergwelt-Baildon M, Kääb S, Zimmer R, Bülow RD, von Stillfried S, Boor P, Massberg S, Pekayvaz K, Stark K (2021). Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID-19 from influenza pneumonia. J Thromb Haemost. 19:574-581. PMID 33217134. [A7, B6, Z2]
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