SFB 1123 Atherosclerosis-Mechanisms and Networks of Novel Therapeutic Targets

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PhD Position Lab Megens Duchene

Immunnology Inflammation


The University Hospital of Munich (LMU), is one of the largest and most competitive university hospitals in Germany and Europe. 47 specialized hospitals, departments and institutions harboring excellent research and education provide patient care at the highest medical level with approximately 10.000 employees.

The Institute for Cardiovascular Prevention invites applications for

2 PhD Positions in Immunology/Inflammation (m/f/d) in full-time
(Start: Summer 2022)

We are interested in identifying cellular and molecular pathways implicated in the innate immune response and hematopoiesis of inflammatory diseases, with a special focus on cardiovascular disease. Our group is studying the multifaceted functions of chemokines and in particular atypical chemokine receptors in inflammatory diseases. Additionally, we are investigating the morphology and mechanisms within the bone marrow and the role of hematopoietic cells in cardiovascular disease. To this end, we combine genetically manipulated mouse models (KO, CRE/LOX, CRISPR/Cas9KO), flow cytometry (LSRFortessa X-20, FACSAria), transcriptome and proteome analysis (RNAeq, scRNAseq and Mass spectrometry) and cutting-edge imaging technologies (Thunder, two-photon, confocal, STED, optoacoustic and tissue clearing protocols).

We seek:

• Master’s degree in life sciences, ideally with knowledge of cellular and molecular mechanisms in immunology/inflammation and/or cardiovascular disease.
• Experience in animal experimentation, flow cytometry and/or microscopy imaging is a plus, but not mandatory.
• Curiosity, integrity, team spirit and enthusiasm for science.

We offer:

• Workplace with cutting-edge technology embedded in a stimulating scientific community.
• A dynamic international team.
• Opportunity to join a graduate program with scientific and soft-skills training.
• Salary based on the federal wage agreement (TV-L E13 level)

The projects are funded for 4 years by the DFG Collaborative Research Centre 1123 - Atherosclerosis coordinated by the director of the Institute for Cardiovascular Prevention. You will become an active member of this large-scale collaborative effort, which encompasses a total of 20 multidisciplinary basic and clinical research projects and have the opportunity to join its Graduate Program, which offers doctoral candidates a structured framework for training and supervision.

Please send your application (a merged PDF including letter of motivation, curriculum vitae and contact information of 2-3 referees) to Johan Duchêne and Remco Megens at jduchen@med.lmu.de and remco.megens@med.lmu.de no later than 20th of July 2022 or through our online portal.

Application costs cannot be compensated.